Two people were killed in an accident between two vehicles just before midnight on Saturday on the R334 Rocklands Road near Uitenhage
Police spokesperson, Captain Gerda Swart says it is alleged that the driver of a blue VW Polo, with four passengers and a grey Hyundai Getz, with only a driver, collided.
She says two male occupants of the Polo died at the scene, while four others were taken to a local hospital for medical treatment.
The names of the deceased will be released after their next-of-kin have been informed.
Police are investigating a case of culpable homicide.